Boost profitability with the right separation system

Cell harvesting is a key step in all fermentation-based drug production, and the choice of separation system has great impact on product quality, yield and cost for downstream processing. Alfa Laval has supplied separation systems to the biopharma industry for several decades and we offer disc stack separators for all types of biopharma applications. We understand your challenges and regardless of which cell type your process uses and the size of your project, our team of application specialists tailor the perfect separation solution for you.

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Discuss the possibilities to improve cell harvesting in your plant with one of our biopharma experts.

Culturefuge range — gentle efficiency

Our Culturefuge range was specifically developed for processes using mammalian cell cultures. Thanks to its unique design, a Culturefuge separates fragile cells from the broth very gently, minimizing the risk for cell lysis and product contamination.

  • Gentle cell handling minimizes the need for complex downstream processing, resulting in low production cost
  • Fully hermetic design
  • Hygienic design, fully steam sterilizable and CIP-able
  • Fully compliant with FDA regulations
  • Meets the most stringent cGMP requirements
  • Easy scale-up thanks to broad model range
  • Compact
  • Low energy consumption
  • Flexible, can handle multiple product lines
  • Unique patented design with unrivalled performance


Culturefuge 400

Boosting the Alfa Laval MB 601

Alfa Laval MB 601 is the first disc stack separator for the biopharma industry that features our patented integral discs. This ground-breaking technology offers several benefits:

  • Increased separation capacity
  • Raised separation performance
  • Improved hygiene, making cleaning faster and easier

The MB 601 is designed for gentle product treatment and is fully hermetic. It complies with the hardest industry requirements and target applications are processes involving cell cultures, bacteria, rDNA products and vaccines.

Learn more

Please contact us to learn more about the new MB 601.

MB 601

Let’s find the perfect separation equipment for you

There are many factors to consider when choosing cell harvesting centrifuge: the type of cells, cell concentration in the broth, system capacity, future production scale-up, the biosafety level and possible confinement requirements. Our experts can help you select the perfect separation system for your process. We make sure your new equipment meets all your requirements and deliver optimum product quality, production yield and performance. Learn more about our separator models below.   

Patient safety comes first

Our first priority is always the safety of the patients, and every detail of our biopharma separation systems is designed with this in mind. Our solutions comply with the highest manufacturing standards for hygiene, cleanability, traceability, documentation, system changes and validation. We have long experience of supplying centrifugal equipment to the pharmaceuticals industry and have the regulatory expertise and organizational tools to manage all requirements for cGMP compliance. We provide validations, certificates and documentation that comply with the most stringent industry demands. Our in-house Factory Acceptance Test (FAT) lab lets us validate each system before delivery and we can also provide additional validation services if required.


Patient safety

Explore the possibilities

The Alfa Laval Explorer programme lets you try and evaluate our disc stack separation systems at your site. This lets you test the performance of the equipment under your specific process conditions. Please contact us to set up a test run.


Reliable performance

With Alfa Laval as your service partner you have the full support of our global network of dedicated service experts. We offer a wide range of services spanning the entire lifetime of your separation system, such as upgrades that increase separation performance, monitoring systems and audits. Our experts train your operators to run and maintain your system in an optimal way to maximize its performance. When needed, our distribution network quickly supplies spare parts with all the necessary compliance certificates. 


Learn more about Alfa Laval Service

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